Police said the officers were responding to an alleged domestic violence incident at Larapinta Valley Town Camp at about 8:30pm when a group of up to 20 people attacked them.
A male officer was admitted to hospital for a knee injury while a female officer narrowly escaped injury when one attacker swung a wheel spanner at her head.
Alice Springs Acting Superintendent Scott Manley said the officers sought cover in a nearby building until support arrived.
“While attempting to take the woman into custody, it’s alleged that a group of intoxicated persons from nearby residences converged on them,” he said.
“This morning we’ve had a coordinated response from crime and response members to identify all the involved offenders … we’d be looking at charges of assault police and damage to property.
“We condemn this conduct as totally unacceptable, the public expect that their emergency responders should be able to attend and ensure a safe community without being obstructed or put in harm’s way.”
But he said police generally had a good working relationship with the town camps around Alice Springs and that incidents like this did not reflect the behaviour of the wider community.
Northern Territory Police Association president Paul McCue said the frequency of serious assaults on police officers around Alice Springs was increasing.
“We’ve had to see two officers literally run for their lives and abandon their vehicle for simply responding to a job,” he said.
“It’s going to get to a point where officers are going to need several vehicles to go when there’s an incident of that nature.
“The last thing we want to see is anyone in the community put at risk simply because of a few fools that take it upon themselves to attack officers doing their job.”